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Publikationen

Wissenschaftliche Publikationen & Reviews

Publikationen

  1. Caldéron C, Rubarth L, Cebo M, Merfort I, Lämmerhofer M. Lipid atlas of keratinocytes and betulin effects on its lipidome profiled by comprehensive UHPLC-MS/MS; Proteomics 20:21900113 (2020)
  2. Kreisel W, Schaffner D, Lazaro A, Trebicka J, Merfort I, Schmitt-Graeff, Deibert P. Phosphodiesterases in the liver as potential therapeutic targets of cirrhotic portal hypertension; Int J Mol Sciences 21: 6223 (2020)
  3. Rex J, Lutz A, Faletti LA, Albrecht U, Thomas M, Bode JG, Borner C, Sawodny O, Merfort I. Il-1b and TNFa differently influence NF-kB activity and FasL-induced apoptosis in primary murine hepatocytes during LPS-induced inflammation; Front Physiol, Sect Syst Biol 10:117 (2019)
  4. De Ford C, Penchalaiahk K, Kreft A, Humar M, Heydenreuter W, Kangani M, Sieber SA, Tietze LF, Merfort I. Bifunctional duocarmycin analogues as inhibitors of protein tyrosine kinases; J Nat Prod 82: 16-26 (2019)
  5. Contini C, Jansen M, König B, Markfeld-Erol F, Kunze M, Zschiedrich S, Massing U, Merfort I, Prömpeler H, Pecks U, Winkler K, Pütz G. Lipoprotein turnover and possible remnant accumulation in preeclampsia: Insights from the Freiburg preeclampsia H.E.L.P.-apheresis study; Lipids Health Dis 17:49 (2018)
  6. Popadiƈ D, Heßelbach K, Richter-Brockmann S, Kim GJ, Flemming S, Sschmidt-Heck W, Häupl T, Bonin M, Dornhof R, Achten C, Günther S, Humar M,* Merfort I.* Gene expression profiling of human bronchial epithelial cells exposed to fine particulate matter (PM2.5) from biomass combustion; Toxicol Appl Pharmacol 347, 10-22 (2018), * both authors contributed equally to the work
  7. Faletti L, Peintner L, Neumann S, Sandler S, Grabinger T, McNelly S, Merfort I, Huang CH, Tschaharganeth D, Kang TW, Heinzmann F, D'Artista L, Maurer U, Brunner T, Lowe S, Zender L, Borner C. TNFα sensitizes hepatocytes to FasL-induced apoptosis by NFκB-mediated Fas upregulation; Cell Death Dis 9:909 (2018)
  8. Schaffner D, Lazaro A, Deibert P, Hasselblatt P, Stoll P, Fauth L, Baumstark MW, Merfort I, Schmitt-Graeff A, Kreisel W. Analysis of the nitric oxide-cyclic guanosine monophosphate pathway in experimental liver cirrhosis suggests phosphodiesterase-5 as potential target to treat portal hypertension; World J Gastroenterol 24, 4356-4368 (2018)
  9. Dornhof R, Maschowski C, Osipova A, Giere R, Seidl M, Merfort I,* Humar M.* Stress fibers, autophagy and necrosis by persistent exposure to PM2.5 from biomass combustion; PLoS One 12:e0180291 (2017), * both authors contributed equally to the work
  10. Greule A, Martolt M, Deubel D, Peintner I, Zhang S, Jessen-Trefzer C, De Ford C, Burschel S, Li SM, Friedrich T, Merfort I, Luedeke S, Bisel P, Müller M, Paululat T, Bechthold A. Wide distribution of foxicin biosynthetic gene clusters in Streptomyces strains - An unusual secondary metabolite with various properties; Front Microbiol 8:221 (2017)
  11. Schaffner D, von Elverfeldt D, Deibert P, Lazaro A, Merfort I, Lutz L, Neubauer J, Baumstark MW, Kreisel W, Reichardt W. Phase-contrast MR flow imaging: A tool to determine hepatic hemodynamics in rats with a healthy, fibrotic, or cirrhotic liver; J Magn Reson Imaging 46, 1526-1534 (2017)
  12. Nicolaus C, Junghanns S, Hartmann A, Murillo R, Ganzera M, Merfort I. In vitro studies to evaluate the wound healing properties of Calendula officinalis extracts; J Ethnopharmacol 196: 94-103 (2017)
  13. Ueck C, Volksdorf T, Houdek P, Vidal-Y-Sy S, Sehner S, Ellinger B, Lobmann R, Larena-Avellaneda A, Reinshagen K, Ridderbusch I, Kohrmeyer K, Moll I, Daniels R, Werner P, Merfort I, Brandner JM. Comparison of in-vitro and ex-vivo wound healing assays for the investigation of diabetic wound healing and demonstration of a beneficial effect of a triterpene extract; PLoS One 12:e0169028 (2017)
  14. Heßelbach K, Kim GJ, Flemming S, Häupl T, Bonin M, Dornhof R, Günther S, Merfort I,* Humar M.* Disease relevant modifications of the methylome and transcriptome by particulate matter (PM2.5) from biomass combustion; Epigenetics 12, 779-792 (2017), * both authors contributed equally to the work
  15. Cursino LM, Lima NM, Murillo R, Nunez CV, Merfort I, Humar M. Isolation of flavonoids from Deguelia duckeana and their effect on cellular viability, AMPK, eEF2, eIF2 and eIF4E; Molecules 21:192 (2016)
  16. Kadioglu O, Jacob S, Bohnert S, Naß J, Saeed ME, Khalid H, Merfort I, Thines E, Pommerening T, Efferth T. Evaluating ancient Egyptian prescriptions today: Anti-inflammatory activity of Ziziphus spina-christi; Phytomedicine 23, 293-306 (2016)
  17. Wardecki T, Werner P, Thomas M, Templin MF, Schmidt G, Brandner JM, Merfort I. Influence of birch bark triterpenes on keratinocytes and fibroblasts from diabetic and nondiabetic donors; J Nat Prod 79, 1112-1123 (2016)
  18. Nicolaus C, Sievers-Engler A, Murillo R, D'Ambrosio M, Lämmerhofer M, Merfort I. Mastering analytical challenges for the characterization of pentacyclic triterpene mono- and diesters of Calendula officinalis flowers by non-aqueous C30 HPLC and hyphenation with APCI-QTOF-MS; J Pharm Biomed Anal 118, 195-205 (2016)
  19. De Ford C, Heidersdorf B, Haun F, Murillo R, Friedrich T, Borner C, Merfort I. The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling; Cell Death Dis 7:e2070 (2016)
  20. Fronza M, Muhr C, Da Silveira DS, Sorgi CA, Rodrigues SF, Farsky SH, Paula-Silva FW, Merfort I, Faccioli LH. Hyaluronidase decreases neutrophils infiltration to the inflammatory site; Inflamm Res 65, 533-542 (2016)
  21. Baudiß K, Ayata CK, Lazar Z, Cicko S, Beckert J, Meyer A, Zech A, Vieira RP, Bittman R, Gomez-Munoz A, Merfort I, Idzko M. Ceramide-1-phosphate inhibits cigarette smoke-induced airway inflammation; Eur Resp J 45, 1669-1680 (2015)
  22. Lutz A, Sanwald J, Thomas M, Feuer R, Sawodny O, Ederer M, Borner C, Humar M, Merfort I. Interleukin-1 beta enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes; PLos One 9:e115603 (2015)
  23. Patel H, Lucas X, Bendik I, Günther S, Merfort I. Target fishing by cross-docking to explain polypharmacological effects; ChemMedChem 10, 1209-1217 (2015)
  24. De Ford C, Calderón C, Sehgal P, Fedosova NU, Murillo R, Olesen C, Nissen P, Møller JV, Merfort I. Discovery of tricyclic clerodane diterpenes as sarco/endoplasmic reticulum Ca(2+)-ATPase inhibitors and structure-activity relationships; J Nat Prod 78, 1262-70 (2015)
  25. De Ford C, Ulloa JL, Catalan CA, Grau A, Martino VS, Muschietti LV, Merfort I. The sesquiterpene lactone polymatin B from Smallanthus sonchifolius induces different cell death mechanisms in three cancer cell lines; Phytochemistry 117, 332-9 (2015)
  26. Wardecki T, Brötz E, De Ford C, von Loewenich FD, Rebets Y, Tokovenko B, Luzhetskyy A, Merfort I. Endophytic streptomyces in the traditional medicinal plant Arnica montana L.: Secondary metabolites and biological activity; Antonie Van Leeuwenhoek 108, 391-402 (2015)
  27. Calderón C, De Ford C, Merfort I, Murillo R. Cytotoxic clerodane diterpenes from Zuelania guidonia; J Nat Prod 77, 455-463 (2014)
  28. Ebeling S, Naumann K, Pollok S, Wardecki T, Vidal-Y-Sy S, Nascimento JM, Boerries M, Schmidt G, Brandner JM, Merfort I. From a traditional medicinal plant to a rational drug: Understanding the clinically proven wound healing efficacy of birch bark extract; PLoS One 9:e86147 (2014)
  29. Fronza M, Caetano GF, Leite MN, Bitencourt CS, Paula-Silva FW, Andrade TA, Frade MA, Merfort I, Faccioli LH. Hyaluronidase modulates inflammatory response and accelerates the cutaneous wound healing; PLoS One 9:e112297 (2014)
  30. Patel H, Grüning BA, Günther S, Merfort I. PyWATER: a PyMOL plug-in to find conserved water molecules in proteins by clustering; Bioinformatics 30, 2978-2980 (2014)
  31. Gründemann C, García-Käufer M, Sauer B, Stangenberg E, Könczöl M, Merfort I, Zehl M, Huber R. Traditionally used Veronica officinalis inhibits proinflammatory mediators via the NF-kB signalling pathway in a human lung cell line; J Ethnopharmacol 145, 118-126 (2013)
  32. Könczöl M, Weiss A, Gminski R, Merfort I, Mersch-Sundermann V. Oxidative stress and inflammatory response to printer toner particles in human epithelial A549 lung cells; Toxicol Lett 216, 171-180 (2013)
  33. Könczöl M, Weiss A, Stangenberg E, Gminski R, García-Käufer M, Giere R, Merfort I, Mersch-Sundermann V. Cell-cycle changes and oxidative stress response to magnetite in A549 human lungcCells; Chem Res Toxicol 26, 171-180 (2013)
  34. Vassallo A, De Tommasi N, Merfort I, Sanogo R, Severino L, Pelin M, Della Loggia R, Tubaro A, Sosa S. Steroids with anti-inflammatory activity from Vernonia nigritiana Oliv. & Hiern; Phytochemistry 96, 288-298 (2013)
  35. Senger C, Grüning BA, Erxleben A, Döring K, Patel H, Flemming S, Merfort I, Günther S. Mining and evaluation of molecular relationships in literature; Bioinformatics 28, 709-714 (2012)
  36. Millet A, Lamy E, Jonas D, Stintzing F, Mersch-Sundermann V, Merfort, I. Fermentation enhances the biological activity of Allium bulb extracts; J Agric Food Chem 60, 2148-2156 (2012)
  37. Fronza M, Lamy E, Günther S, Heinzmann B, Laufer S, Merfort, I. Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of action; Phytochemistry 78, 107-119 (2012)
  38. Lingott T, Merfort I, Steinbrecher T. Free energy calculations on snake venom metalloproteinase BaP1; Chem Biol Drug Des 79, 990-1000 (2012)
  39. Naumann K, Schmich K, Jäger C, Kratz F, Merfort I. Noxa/Mcl-1 balance influences the effect of the proteasome inhibitor MG-132 in combination with anticancer agents in pancreatic cancer cell lines; Anticancer Drugs 23, 614-626 (2012)
  40. Könczöl M, Goldenberg E, Ebeling S, Schäfer B, García-Käufer M, Gminski R, Grobety B, Rothen-Rutisberger B, Merfort I, Giere R, Mersch-Sundermann V. Cellular uptake and toxic effects of fine and ultrafine metal-sulfate particles in human A549 lung epithelial cells; Chem Res Toxicol 25, 2687-2703 (2012)
  41. Schmich K, Schlatter R, Corazza N, Ferreira KS, Ederer M, Brunner T, Borner C, Merfort I. Tumor necrosis factor alpha sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner; Hepatology.53, 282-292 (2011)
  42. Fronza M, Murillo R, Slusarczyk S, Adams M, Hamburger M, Heinzmann B, Laufer S, Merfort I. In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica; Bioorg Med Chem 19, 4876-4881 (2011)
  43. Könczöl M, Ebeling S, Goldenberg E, Treude F, Gminski R, Giere R, Grobety B, Rothen-Rutishauser B, Merfort I, Mersch-Sundermann V. Cytotoxicity and genotoxicity of size-fractionated iron oxide (magnetite) in A549 human lung epithelial cells: Role of ROS, JNK, and NF-kB; Chem Res Toxicol 24, 1460-1475 (2011)
  44. Seidel P, Roth M, Ge Q, Merfort I, S'ng CT, Ammit AJ. IkB-alpha glutathionylation and reduced histone H3 phosphorylation inhibit eotaxin and RANTES; Eur Respir J 38, 1444-1452 (2011)
  45. Schmidt CA, Murillo R, Heinzmann B, Laufer S, Wray V, Merfort I. Structural and conformational analysis of proanthocyanidins from Parapiptadenia rigida and their wound-healing properties; J Nat Prod 74, 1427-1436 (2011)
  46. Schlatter R, Schmich K, Lutz A, Trefzger J, Sawodny O, Ederer M, Merfort I. Modeling the TNFα-induced apoptosis pathway in hepatocytes; PLoS One 6:e18646 (2011)
  47. Vuckoviƈ I, Vujisic L, Klaas CA, Merfort I, Milosavljevic S. NF-kB DNA binding activity of sesquiterpene lactones from Anthemis arvensis and Anthemis cotula; Nat Prod Res 25, 800-805 (2011)
  48. Shin EM, Zhou HY, Xu GH, Lee SH, Merfort I, Kim YS. Anti-inflammatory activity of hispidol A 25-methyl ether, a triterpenoid isolated from Ponciri immaturus fructus; Eur J Pharmacol 627, 318-324 (2010)
  49. Escandell JM, Recio MC, Giner RM, Manez S, Cerda-Nicolas M, Merfort I, Rios JL. Inhibition of delayed-type hypersensitivity by cucurbitacin R through the curbing of lymphocyte proliferation and cytokine expression by means of nuclear fctor AT translocation to the nucleus; J Pharmacol Exp Ther 332, 352-363 (2010)
  50. Geller F, Schmidt C, Göttert M, Fronza M, Schattel V, Heinzmann B, Werz O, Flores EM, Merfort I, Laufer S. Identification of rosmarinic acid as the major active constituent in Cordia Americana; J Ethnopharmacol 128, 561-566, 2010
  51. Wölfle U, Simon-Haarhaus B, Merfort I, Schempp CM. Reseda luteola L. extract displays antiproliferative and pro-apoptotic activities that are related to its major flavonoids; Phytother Res 24, 1033-1036 (2010)
  52. Sparna T, Retey J, Schmich K, Albrecht U, Naumann K, Gretz N, Fischer HP, Bode JG, Merfort I. Genome-wide comparison between IL-17 and combined TNF-alpha/IL-17 induced genes in primary murine hepatocytes; BMC Genomics 11, 226 (2010)
  53. Millet A, Stintzing F, Merfort I. Flavonol quantification and stability of phenolics in fermented extracts from fresh Betula pendulaLleaves; J Pharm Biomed Anal 53, 137-144 (2010)
  54. Büchele B, Zugmaier W, Lunov O, Syrovets T, Merfort I, Simmet T. Surface plasmon resonance analysis of nuclear factor-kappaB protein interactions with the sesquiterpene lactone helenalin; Anal Biochem 401, 30-37 (2010)
  55. Zellmer S, Schmidt-Heck W, Godoy P, Weng H, Meyer C, Lehmann T, Sparna T, Schormann W, Hammad S, Kreutz C, Timmer J, von Weizsäcker F, Thürmann PA, Merfort I, Guthke R, Dooley S, Hengstler JG, Gebhardt R. Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes; Hepatology 52, 2127-2136 (2010)
  56. Li Z, Merfort I, Reich E. High performance thin layer chromatography for quality control of multi-component herbal drugs: Example Cangztin Xianglian San; J AOAC International 93, 1390-1398 (2010)
  57. Wallnoeffer HG, Lingott T, Gutiérrez JM, Merfort I, Liedl KR. Backbone flexibility controls the activity and specificity of a protein-protein interface: Specificity in snake venom metalloproteases; J Am Chem Soc 132, 10330-10337 (2010)
  58. Seidel P, Merfort I, Tamm M, Roth M. Inhibition of NF-kB and AP-1 by dimethylfumarate correlates with down-regulated IL-6 secretion and proliferation in human lung fibroblasts; Swiss Med Wkly 140:w13132. (2010)
  59. Göttert M, Schattel V, Koch P, Merfort I, Laufer S. Biological evaluation and structural determinants of p38a mitogen-activated-protein kinase and c-Jun-N-terminal kinase 3 inhibition by flavonoids; Chembiochem 11, 2579-2588 (2010)
  60. Lass C, Merfort I, Martin SF. In vitro and in vivo analysis of pro- and anti-inflammatory effects of weak and strong contact allergens; Exp Dermatol 19, 1007-1013 (2010)
  61. Shin EM, Kim S, Merfort I, Kim YS. Glycyrol induces apoptosis in human Jurkat T cell lymphocytes via the Fas-FasL/caspase-8 pathway; Planta Med 77, 242-247 (2010)
  62. Schmidt CA, Murillo R, Bruhn T, Bringmann G, Göttert M, Heinzmann B, Brecht V, Laufer S, Merfort I. Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties; J Nat Prod 73, 2035-2041 (2010)
  63. Millet A, Stintzing F, Merfort I. Validation of a GC-FID method for rapid quantification of nicotine in fermented extracts prepared from Nicotiana tabacum fresh leaves and studies of nicotine metabolites; J Pharm Biomed Anal 49,1166-1171 (2009)
  64. Schmidt C, Fronza M, Göttert M, Geller F, Luik S, Flores EM, Bittencourt CF, Zanetti GD, Heinzmann BM, Laufer S, Merfort I. Biological studies on Brazilian plants used in wound healing; J Ethnopharmacol 22, 523-532 (2009)
  65. Lingott T, Schleberger C, Gutiérrez JM, Merfort I. High-resolution crystal structure of the snake venom metalloproteinase BaP1 complexed with a peptidomimetic: Insight into inhibitor binding; Biochemistry 48, 6166-6174 (2009)
  66. Jäger C, Hrenn A, Zwingmann J, Suter A, Merfort I. Phytomedicines prepared from Arnica flowers inhibit the transcription factors AP-1 and NF-kB and modulate the activity of MMP1 and MMP13 in human and bovine chondrocytes; Planta Med 75, 1319-1325 (2009)
  67. Seidel P, Merfort I, Hughes JM, Oliver BG, Tamm M, Roth M. Dimethylfumarate inhibits NF-kB function at multiple levels to limit airway smooth muscle cell cytokine secretion; Am J Physiol Lung Cell Mol Physiol 297, L326-39 (2009)
  68. Altevogt D, Hrenn A, Kern C, Clima L, Bannwarth W, Merfort I. A new assay format for NF-kB based on a DNA triple helix and a fluorescence resonance energy transfer; Org Biomol Chem 7, 3934-3939 (2009)
  69. Misiek M, Williams J, Schmich K, Hüttel W, Merfort I, Salomon CE, Aldrich CC, Hoffmeister D. Structure and cytotoxicity of arnamial and related fungal sesquiterpene aryl esters; J Nat Prod 72, 1888-1891 (2009)
  70. Fronza M, Heinzmann B, Hamburger M, Laufer S, Merfort I. Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts; J Ethnopharmacol 126, 463-467 (2009)
  71. Casetti F, Jung W, Wölfle U, Reuter J, Neumann K, Gilb B, Wähling A, Wagner S, Merfort I. Schempp CM. Topical application of solubilized Reseda luteola extract reduces ultraviolet B-induced inflammation in vivo; J Photochem Photobiol B 96, 260-265 (2009)
  72. Schlatter R, Schmich, K, Avalos Vizcarra I, Scheurich P, Sauter T, Borner C, Ederer M, Merfort I, Sawodny O. On/off and beyond. A Boolean model of apoptosis; PLoS Comput Biol 5:e1000595 (2009)
  73. Jocher A, Nist G, Weiss JM, Wetzel D, Merfort I, Jakob T, Schempp CM. Allergenic potential of Arnica-containing formulations in Arnica-allergic patients; Contact Dermatitis 61, 304-306 (2009)
  74. Steinbrecher T, Hrenn A, Dormann K, Merfort I, Labahn A. Bornyl-(3,4,5-trihydroxy)-cinnamate - an optimized human neutrophil elastase inhibitor designed by free energy calculations; Biorg Med Chem 16, 2385-2390 (2008)
  75. Wagner S, Arce R, Murillo R, Terfloth L, Gasteiger J, Merfort I. Neural networks as valuable tools to differentiate between sesquiterpene lactones’ inhibitory activity on serotonin release and on NF-kB; J Med Chem 13, 1324-1332 (2008)
  76. Götschel F, Kern C, Lang S, Sparna T, Markmann C, Schwager J, McNelly S, von Weizsäcker F, Laufer S, Hecht A, Merfort I. The inhibition of GSK differentially modulates NF-kB, CREB, AP-1 and β-catenin in signaling in hepatocytes, but fails to promote TNF-α-induced apoptosis; Exper Cell Res 314, 1351-1366 (2008)
  77. Soltau J, Zirrgiebel U, Esser N, Schächtele C, Totzke F, Unger C, Merfort I, Drevs J. Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model; Anticancer Res 28, 933-941 (2008)
  78. Lass C, Vocanson M, Wagner S, Schempp CM, Nicolas JF, Merfort I, Martin SF. Anti-inflammatory and immune-regulatory mechanisms prevent contact hypersensitivity to Arnica montana L.; Exp Dermatol 17, 849-857 (2008)
  79. Arakawa NS, Schorr K, Ambrosio SR, Merfort I, Da Costa FB. Further sesquiterpene lactones from Viguiera robusta and the potential anti-inflammatory activity of a heliangolide: Inhibition of human neutrophil elastase release; Z Naturforsch 63, 533-538 (2008)
  80. Shin EM, Zhou HY, Guo LY, Kim JA, Lee SH, Merfort I, Kang SS, Kim HS, Kim S, Kim YS. Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages; Int Immunopharmacol 8, 1524-1532 (2008)
  81. Wagner S, Urena A, Reich E, Merfort I. Validated HPTLC methods for the determination of salicin in Salix sp. and of harpagoside in Harpogophytum procumbens; J Pharm Biomed Anal 48, 587-591 (2008)
  82. Walter D, Schmich K, Vogel S, Pick R, Kaufmann T, Hochmuth FC, Haber A, Neubert K, McNelly S, von Weizsäcker F, Merfort I, Maurer U, Strasser A, Borner C. Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes; Hepatology 48, 1942-1953 (2008)
  83. Lindenmeyer MT, Kern C, Sparna T, Donauer J, Wilpert J, Schwager J, Porath D, Kreutz C, Timmer J, Merfort I. Microarray analysis reveals influence of the sesquiterpene lactone parthenolide on gene transcription profiles in human epithelial cells; Life Sci 80, 1608-1618 (2007)
  84. Schorr K, Merfort I, Da Costa, FB. A novel dimeric melampolide and further terpenoids from Smallanthus sonchifolius (Asteraceae) and the inhibition of the transcription factor NF-kB; Nat Prod Commun 2, 367-374 (2007)
  85. Lopez-Anton N, Hermann C, Murillo R, Merfort I, Wanner G, Vollmar AM, Dirsch VM. Sesquiterpene lactones induce distinct forms of cell death that modulate human monocyte-derived macrophage responses; Apoptosis 12, 141-153 (2007)
  86. Huber R, von Ditfurth A, Amann F, Güthlin C, Rostock M, Trittler R, Kümmerer K, Merfort I. Tormentil for active ulcerative colitis - an open-label, dose-escalating study; J Clin Gastroenterol 41, 834-838 (2007)
  87. Wagner S, Merfort I. Skin penetration behaviour of sesquiterpene lactones from different Arnica preparations using a validated GC-MSD method; J Pharm Biomed Anal 43, 32-38 (2007)
  88. Kos O, Lindenmeyer MT, Tubaro A, Sosa S, Merfort I. New sesquiterpene lactones from Arnica tincture prepared fromfFresh flowerheads of Arnica montana; Planta Med 71, 1044-1052 (2006)
  89. Kos O, Castro V, Murillo R, Poveda L, Merfort I. Ent-Kaurane glycosides and sesquiterpene lactones from the hirsutinolide type from Vernonia triflosculosa. Phytochemistry 67, 62-69 (2006)
  90. Grassl GA, Fessele S, Merfort I, Lindenmeyer MT, Castro V, Murillo R, Nelson PJ, Autenrieth IB. Sesquiterpene lactones inhibit Yersinia invasin protein-induced IL-8 and MCP-1 production in epithelial cells; Int J Med Microbiol 295, 531-538 (2006)
  91. Wagner S, Hofmann A, Siedle B, Terfloth L, Merfort I, Gasteiger J. Development of a structural model for NF-kB inhibition of sesquiterpene lactones using self-organizing neutral networks; J Med Chem 49, 2241-2252 (2006)
  92. Stefani R, Schorr K, Tureta, JM, Vichnewski W, Merfort I, Da Costa FB. Sesquiterpene lactones from Dimerostema species (Asteraceae) and in vitro potential anti-inflammatory activities; Z Naturforsch C 61c, 647-652 (2006)
  93. Hrenn A, Steinbrecher T, Labahn A, Schwager J, Schempp CA, Merfort I. Plant phenolics inhibit neutrophil elastase and proliferation of keratinocytes; Planta Med 72, 1127-1131 (2006)
  94. Lindenmeyer MT, Hrenn A, Kern C, Castro V, Murillo R, Müller S, Laufer S, Schulte-Mönting J, Siedle B, Merfort I. Sesquiterpene lactones as inhibitors of Il-8 expression in Hela cells; Bioorg Med Chem 14, 2487-2497 (2006)
  95. Spitaler R, Schlorhaufer PD, Elmerer EP, Merfort I, Bortenschlager S, Stuppner H, Zidorn C. Altitudinal variation of secondary metabolite profiles in flowerheads of Arnica montana cv ARBO. Phytochemistry 67, 409-417 (2006)
  96. Klingmüller U, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Götschel F, Hecht A, Walter D, Egger L, Neubert K, Borner C, Brulport M, Schormann W, Sauer C, Baumann F, Preis R, McNelly S, Godoy P, Wiercinska E, Ciuclan L, Edelmann J, Zeilinger K, Heinrich M, Zanger UM, Gebhardt R, Maiwald T, Heinrich R, Timmer J, von Weiszsäcker F, Hengstler JG. Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways; Proc Syst Biol 153, 433-447 (2006)
  97. Endale A, Wray V, Murillo R, Schmidt PC, Merfort I. Hopane-type saponins from the seeds of Glinus lotoides; J Nat Prod 68, 443-446 (2005)
  98. Nunez V, Castro V, Murillo R, Ponce-Soto A, Merfort I, Lomonte B. Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: Isolation of 4-nerolidyl-catechol as active principle; Phytochemistry 6, 1017-1025 (2005)
  99. Schorr K, Rott A, Da Costa FB, Merfort I. Optimisation of a human neutrophil elastase assay and investigation of the effect of sesquiterpene lactones; Biologicals 33, 175-184 (2005)
  100. Melo MM, Habermehl GG, Castro V, Merfort I. Topic utilisation of a sesquiterpene lactone from Milleria quinqueflora on treatment of Bothops envenomation in rabbits; Arq Bras Med Veterinaria 57, 548-552 (2005)
  101. Wagner S, Kratz F, Merfort I. In-vitro behaviour of sesquiterpene lactones and sesquiterpene lactone-containing plant preparations in human blood, plasma and human serum albumin solutions; Planta Med 70, 227-233 (2004)
  102. Lindenmeyer MT, García-Piñeres AJ, Castro V, Merfort I. Sesquiterpene lactones inhibit luciferase, but not ß-galactosidase activity in vitro and ex-vivo; Anal Biochem 328, 147-154 (2004)
  103. Müller S, Murillo R, Castro V, Brecht V, Merfort I. Sesquiterpene lactones from Montanoa hibiscifolia that inhibit the transcription factor NF-kB; J Nat Prod 67, 622-630 (2004)
  104. García-Piñeres AJ, Lindenmeyer MT, Merfort I. Role of cysteine residues of p65/NF-kB on the inhibition by sesquiterpene lactones and N-ethylmaleimide, and on its transactivating potential; Life Sci 75, 841-856 (2004)
  105. Wagner S, Suter A, Merfort I. Skin penetration studies of Arnica preparations and of their sesquiterpene lactones; Planta Med 70, 897-903 (2004)
  106. Siedle B, García-Piñeres AJ, Murillo R, Schulte-Mönting J, Castro V, Rüngeler P, Klaas CA, Da Costa FB, Kisiel W, MerfortT I. Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-kB; J Med Chem 47, 6042-6054 (2004)
  107. Siedle B, Gustavsson L, Johansson S, Murillo R, Castro V, Bohlin L, Merfort I. The effect of sesquiterpene lactones on the release of human neutrophil elastase; Biochem Pharmacol 65, 897-903 (2003)
  108. Humar M, García-Piñeres AJ, Castro V., Merfort I. Effect of sesquiterpene lactones on the T-cell activation and IL-2 production of T-lymphocytes in whole blood; Biochem Pharmacol 65, 1551-1563 (2003)
  109. Müller S, Tirapelli CR, De Oliveira AM, Murillo R, Castro V, Merfort I. Studies of ent-kaurane diterpenes from Oyedaea verbesinoides for their inhibitory activity on vascular smooth muscle contraction; Phytochemistry 63, 391-396 (2003)
  110. Siedle B, Murillo R, Hucke O, Labahn A, Merfort I. Structure activity relationship studies of cinnamic acid derivatives as inhibitors of human neutrophil elastase revealed by ligand docking calculations; Pharmazie 58, 337-339 (2003)
  111. Petrovic SD, Dobric S, Bokonjic D, Niketic M, García-Piñeres AJ, Merfort I. Evaluation of Tanacetum larvatum for an anti-inflammatory activity and for the protection against Indomethacin-induced ulcerogenesis in Rats; J Ethnopharmacol 87, 109-113 (2003)
  112. Klaas CA, Wagner G, Laufer S, Sosa S, Della Loggia R, Bomme U, Pahl HL, Merfort I. Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers; Planta Med 68, 385-391 (2002)
  113. Siedle B, Cisielski S, Murillo R, Löser B, Castro V, Klaas CA, Hucke O, Labahn A, Melzig MF, Merfort I. Sesquiterpene lactones as inhibitors of human neutrophil elastase; Bioorg Med Chem 10, 2855-2861 (2002)
  114. Aguilar JL, Rojas P, Marcelo A, Plaza A, Bauer R, Reiniger E, Klaas CA, Merfort I. Anti-inflammatory activity of two different extracts of Uncaria tomentosa; J Ethnopharmacol 81, 271-276 (2002)
  115. Schorr K, García-Piñeres AJ, Siedle B, Merfort I, Da Costa FB. Guaianolides from Viguiera gardneri inhibit the transcription factor NF-kappaB; Phytochemistry 60, 733-740 (2002)
  116. Rüngeler P, Brecht V, Tamayo-Castillo G, Merfort I. New germacranolides from Mikania guaco; Phytochemistry 56, 475-489 (2001)
  117. Zorn, B, García-Piñeres AJ, Castro V, Murillo R, Mora G, Merfort I. 3-Desoxyanthocyanidins from Arrabidaea chica; Phytochemistry 56, 831-835 (2001)
  118. Koch E, Klaas CA, Rüngeler P, Castro V, Mora G, Vichnewski W, Merfort I. Anti-inflammatory effects of sesquiterpene lactones by inhibition of cytokine production and lymphocyte proliferation; Biochem Pharmacol 62, 795-801 (2001)
  119. García-Piñeres AJ, Castro V, Mora G, Schmidt TJ, Strunck E, Pahl HL, Merfort I. Cysteine 38 in p65/NF-kB plays a crucial role in DNA binding inhibition by sesquiterpene lactones; J Biol Chem 276, 39113-39720 (2001)
  120. Castro V, Rüngeler P, Murillo R, Hernandez E, Mora G, Pahl HL, Merfort I. Study of sesquiterpene lactones from Milleria quinqueflora on their anti-inflammatory activity using the transcription factor NF-kB as molecular target; Phytochemistry 53, 257-263 (2000)
  121. El-Mousallamy AMD, Hussein SAM, Merfort I, Nawwar MAM. Unusual phenolic glycosides from Cotoneaster orbicularis; Phytochemistry 5, 699-704 (2000)
  122. Lyß G, Glasl S, Jurenitsch J, Pahl HL, Merfort I. A sesquiterpene and sesquiterpene lactones from the Achillea millefolium group possess antiinflammatory properties but do not inhibit the transcription factor NF-kB; Pharm Pharmacol Lett 10, 13-15 (2000)
  123. Castro V, Murillo R, Klaas CA, Meunier C, Mora G, Pahl HL, Merfort I. Inhibition of the transcription factor NF-kB by sesquiterpene lactones from Podachaenium eminens; Planta Med 66, 591-595 (2000)
  124. Petrovic SD, Gorunovic MS, Wray V, Merfort I. A taraxasterol derivative and phenolic compounds from Hieracium gymnocephalum; Phytochemistry 50, 293-296 (1999)
  125. Petrovic SD, Löscher R, Gorunovic MS, Merfort I. Flavonoid and phenolic acid pattern in seven Hieracium species; Biochem Syst Ecol 27, 651-656 (1999)
  126. Heilmann J, Müller E, Merfort I. Flavonoid glucosides and dicaffeoylquinic acids from flowerheads of Buphthalmum salicifolium; Phytochemistry 51, 713-718 (1999)
  127. Zidorn C, Dirsch VM, Rüngeler P, Sosa S, Della Loggia R, Merfort I, Pahl HL, Vollmar AM, Stuppner H. Antiinflammatory activities of hypocretenolides from Leontodon hispidus; Planta Med 65, 704-708 (1999)
  128. Melzig M, Löser B, Lobitz GO, Tamayo-Castillo G, Merfort I. Inhibition of granulocyte elastase by caffeic acid derivatives; Pharmazie 54, 9 (1999)
  129. Rüngeler P, Castro V., Mora G, Gören N, Vichnewski W, Pahl HL, Merfort I*, Schmidt TJ.* Inhibition of transcription factor NF-kB by sesquiterpene Lactones - a proposed molecular mechanism of action and structure activity relationships; Bioorg Med Chem 7, 2343-2352 (1999) * both authors contributed equally to the work
  130. Lyß G, Schmidt TJ, Pahl HL, Merfort I. Studies for the anti-inflammatory activity of Arnica tincture using the transcription factor NF-kB as molecular target; Pharm Pharmacol Lett 9, 5-8 (1999)
  131. Schmidt TJ, Lyß G, Pahl HL, Merfort I. Helenanolide type sesquiterpene lactones - V. The role of glutathione addition under physiological conditions; Bioorg Med Chem 7, 2849-2855 (1999)
  132. Marzouk MS, El-Toumy SAA, Merfort I, Nawwar MAM. Polyphenolic metabolites of Rhamnus disperma; Phytochemistry 52, 943-946 (1999)
  133. Lobitz GO, Tamayo-Castillo G, Poveda L, Merfort I.: Phytochemical and biological studies on Costa Rican Asteraceae. II. New kaurene derivatives from Mikania vitifolia; Phytochemistry 49, 805-809 (1998)
  134. Lobitz GO, Heilmann J, Zschocke S, Tamayo-Castillo G, Bauer R, Merfort I. Bornyl cinnamate derivatives with anti-inflammatory activity from Verbesina turbacensis; Pharm Pharmacol Lett 8, 115-118 (1998)
  135. Rüngeler P, Lyß G, Castro V, Mora G, Pahl HL, Merfort I. Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kB and enzymes of the arachidonic acid pathway as targets; Planta Med 64, 588-593 (1998)
  136. Lyß G, Knorre A, Schmidt TJ, Pahl HL, Merfort I. The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kB by directly targeting p65; J Biol Chem 273, 33508-33516 (1998)
  137. Merfort I, Pietta PG, Mauri PL, Zini L, Willuhn G: Separation of sesquiterpene lactones from Arnicae flos DAB 10 by micellar electrokinetic chromatography; Phytochem Anal 8, 5-8 (1997)
  138. Merfort I, Wray V, Barakat HH, Hussein SAM, Nawwar MAM, Willuhn G. Three new flavonol triglycosides from Nigella sativa seeds; Phytochemistry 46, 359-363 (1997)
  139. Lobitz GO, Tamayo-Castillo G, Merfort I. Phytochemical and biological studies on Costa Rican Asteraceae. I. Diterpenes and sesquiterpenes from Mikania banisteriae; Phytochemistry 46, 161-164 (1997)
  140. Lyß G, Schmdit TJ, Merfort I, Pahl HL. Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kB; Biol Chem 378, 951-961 (1997)
  141. Barakat HH, Hussein SAM, Marzouk MS, Merfort I, Linscheid M, Nawwar MAM. Polyphenolic metabolites of Epilobium hirsutum; Phytochemistry 46, 935-941 (1997)
  142. Hussein SAM, Barakat HH, Merfort I, Nawwar MAM. Tannins from leaves of Punica granatum; Phytochemistry 45, 819-823 (1997)
  143. Paßreiter CM, Merfort I, Bestendonk C, Willuhn G, Steigel A. 11α,13 and 11ß,13-Dihydro-4H-xanthalongin-4-O-ß-glucopyranoside, new sesquiterpene lactone glycosides from flowers of Arnica amplexicaulis and A. mollis; Planta Med 62, 39-41 (1996)
  144. Merfort I, Heilmann J, Weiss M, Pietta PG, Gardana C. Radical scavenger activity of three metabolites studied by inhibition of chemiluminescence in human PMNs; Planta Med 62, 289-292 (1996)
  145. Merfort I, Willuhn G, Wendisch D, Gondol D. A new 1,5-cis-guaianolide glucoside from flowers of Arnica mollis; Phytochemistry 42, 1093-1095 (1996)
  146. Heilmann J, Merfort I, Weiss M. Radical scavenger activity of different 3’4’,-dihydroxyflavonols and 1,5-dicaffeoylquinic acid studied by inhibition of chemiluminescence; Planta Med 61, 435-438 (1995)
  147. Merfort I, Paßreiter CM, Willuhn G. Flavonoid glycosides from Arnica amplexicaulis and A. mollis; Biochem Syst Ecol 23, 681-682 (1995)
  148. Woerdenbag HJ, Merfort I, Schmidt TJ, Paßreiter CM, Willuhn G, van Uden W, Pras N, Konings AWT. Decreased helenalin-induced cytotoxicity by flavonoids from Arnica as studied in a human lung carcinoma cell line; Phytomedicine 2, 127-132 (1995)
  149. Merfort I. Flavonoid glycosides in Arnica acaulis, subgenus Montana; Biochem Syst Ecol 22, 229 (1994)
  150. Merfort I, Heilmann J, Hagedorn U, Lippold BC. I In vivo skin penetration studies of chamomile flavones; Pharmazie 49, 509-511 (1994)
  151. Pietta P, Mauri P, Bruno A, Merfort I. MEKC as an improved method to detect falsifications in Arnicae Flos DAB 10; Planta Med 60, 369-372 (1994)
  152. Nawwar MAM, Hussein SAM, Merfort I. NMR spectral analysis of polyphenolics from Punica granatum; Phytochemistry 36, 793-798 (1994)
  153. Nawwar MAM, Hussein SAM, Merfort I. Leaf phenolics of Punica granatum; Phytochemistry 37, 1175-1177 (1994)
  154. Woerdenbag HJ, Merfort I, Paßreiter CM, Schmidt TJ, Willuhn G, van Uden W, Pras N, Kampinga HH, Konings WT. Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines; Planta Med 60, 434-437 (1994)
  155. Schmidt TJ, Merfort I, Willuhn G. Gas chromatography - mass spectrometry of flavonoid aglycones. II. Structure-retention relationships and a possibility of differentiation between isomeric 6- and 8-methoxyflavones; J Chromatogr 669, 236-240 (1994)
  156. Skibinski A, Merfort I, Willuhn G. Thirty seven flavonoids from flowers of Arnica longifolia, subgenus Chamissonis; Phytochemistry 37, 1635-1636 (1994)
  157. Schmidt TJ, Merfort I, Matthiesen U. Resolution of complex mixtures of flavonoid aglycones by gas chromatography-mass spectrometry data; J Chromatogr 634, 350-355 (1993)
  158. Merfort I, Wendisch D. Sesquiterpene lactones of Arnica cordifolia, subgenus Austromontana; Phytochemistry 34, 1436-1437 (1993)
  159. Merfort I, Wendisch D. New flavonoid glycosides from Arnicae flos DAB 9; Planta Med 58, 355-357 (1992)
  160. Merfort I, Buddrus J, Nawwar MAM, Lambert J. A new triterpene from the bark of Tamarix aphylla; Phytochemistry 31, 4031-4032 (1992)
  161. Merfort I, Paßreiter CM, Willuhn G. Chromenes from Arnica lessingii and A. amplexicaulis; Biochem Syst Ecol 20, 590 (1992)
  162. Schröder, E, Merfort I. Thermospray LC/MS-studies of flavonoid glycosides from Arnica montana and Arnica chamissonis extracts; Biol Mass Spectrom 20, 11-20 (1991)
  163. Jerga C, Merfort I, Willuhn G. Flavonoidglykoside und andere hydrophile Inhaltsstoffe aus den Blüten von Heterotheca inuloides; Planta Med 56, 339-420 (1990)
  164. Jerga C, Merfort I, Willuhn G. Flavonoidaglyka aus den Blüten von Heterotheca inuloides; Planta Med 56, 122-123 (1990)
  165. Paßreiter CM, Merfort I, Willuhn G. Flavonoids of Arnica sachalinensis, subgenus Andropurpurea; Biochem Sys Ecol 18, 17-18 (1990)
  166. Merfort I, Willuhn G, Jerga C. Arnikablüten DAB 9 - Reinheitsprüfung - Zuordnung und Zusammensetzung der Flavonoidglykosid-Banden im DC und HPLC sowie Vergleich mit den "Mexikanischen Arnikablüten"; Dtsch Apoth Ztg 130, 980-984 (1990)
  167. Merfort I, Wendisch D. Flavonolglucuronide aus den Blüten von Arnica montana; Planta Med 54, 247-250 (1988)
  168. Merfort I. Acetylated and other flavonoid glycosides from Arnica chamissonis; Phytochemistry 27, 3281-3284 (1988)
  169. Ebert M, Merfort I, Willuhn G. Flavonoid distribution in Arnica Subgenera Montana and Austromontana; Phytochemistry 27, 3849- 851 (1988)
  170. Merfort I, Wendisch D. Flavonoidglycoside aus Arnica montana und Arnica chamissonis; Planta Med 53, 434-437 (1987)
  171. Merfort I, Marcinek C, Eggert A. Flavonoid distribution in Arnica Subgenus-Chamissonis; Phytochemistry 25, 2901-2903 (1986)
  172. Merfort I. Flavonoide aus Arnica montana und Arnica chamissonis; Planta Med 136-138 (1985)
  173. Merfort I, Willuhn G. Mariendistel-Tee - als Lebermittel wenig sinnvoll; Dtsch Apoth Ztg 125, 695-696 (1985)
  174. Merfort I, Willuhn G. Zur Toxizität der Früchte von Symphoricarpus albus (Schneebeere) sowie zur Analyse ihrer lipophilen Inhaltsstoffe; Pharm Ztg 130, 2467-2469 (1985)
  175. Merfort I. Phytochemical study of Lucuma mammosa; Fitoterapia 55, 316-317 (1984)
  176. Merfort I. Methylierte Flavonoide aus Arnica montana und Arnica chamissonis; Planta Med 107-108 (1984)
  177. Willuhn G, Merfort I, Matthiesen U. The occurrence of lanosterol and 24-methylenelanost-8-en-3ß-ol in leaves of Symphoricarpus albus; Phytochemistry 22, 137-141 (1983)
  178. Willuhn G, Kresken J, Merfort I. Arnikablüten: Identitäts- und Reinheitsprüfung, Dünnschichtchromatographie der Sesquiterpenlactone und Flavonoide; Dtsch Apoth Ztg 123, 2431-2434 (1983)
  179. Willuhn G, May S, Merfort I. Triterpene und Steroide im Samen von Solanum dulcamara; Planta Med 46, 99-104 (1982)

 Reviews

  1. Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Böttger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Rowlands J, Dahmen U, Damm G, Dirsch O, Donato MT, Dong J, Dooley S, Drasdo D, Eakins R, Ferreira KS, Fonsato V, Fraczek J, Gebhardt R, Gibson A, Glanemann M, Goldring CE, Gomez-Lechon MJ, Groothuis GM, Gustavsson L, Guyot C, Hallifax D, Hammad S, Hayward A, Häussinger D, Hellerbrand C, Hewitt P, Hoehme S, Holzhütter HG, Houston JB, Hrach J, Ito K, Jaeschke H, Keitel V, Kelm JM, Kevin Park B, Kordes C, Kullak-Ublick GA, LeCluyse EL, Lu P, Luebke-Wheeler J, Lutz A, Maltman DJ, Matz-Soja M, McMullen P, Merfort I, Messner S, Meyer C, Mwinyi J, Naisbitt DJ, Nussler AK, Olinga P, Pampaloni F, Pi J, Pluta L, Przyborski SA, Ramachandran A, Rogiers V, Rowe C, Schelcher C, Schmich K, Schwarz M, Singh B, Stelzer EH, Stieger B, Stöber R, Sugiyama Y, Tetta C, Thasler WE, Vanhaecke T, Vinken M, Weiss TS, Widera A, Woods CG, Xu JJ, Yarborough KM, Hengstler JG. Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME; Arch Toxicol 87, 1315-1530 (2013)
  2. Schlatter R, Schmich K, Borner C, Ederer M, Merfort, I.: Systems biology of cell death in hepatocytes; In Systems Biology of Apoptosis, Lavrik I (Ed.), Springer Verlag, 101-123 (2013)
  3. Merfort I. Wechselwirkungen von pflanzlichen Naturstoffen und Elastase; Biospektrum 18, 670-672 (2012)
  4. Merfort I. Perspectives on sesquiterpene lactones in inflammation and cancer; Curr Drug Targets 12, 1560-73 (2011)
  5. Reuter J, Merfort I, Schempp CM. Botanicals in dermatology: An evidence-based review; Am J Clin Dermatol 11, 247-67 (2010)
  6. Merfort I. Arnika - aktueller Stand hinsichtlich Wirksamkeit, Pharmakokinetik und Nebenwirkungen; Z. Phytother 31, 188-192 (2010)
  7. Reuter J, Merfort I, Seelinger G, Wölfle U, Schempp CM. Botanicals in dermatology and skin health; in Botanical Medicine from Bench to Bedside; Cooper R., Kronenberg F. (Eds)., Mary Ann Liebert Inc, New Rochelle, NY, USA, 33-65 (2009)
  8. Seelinger G, Merfort I, Wölfle U, Schempp CM. Anti-carcinogenic effects of the flavonoid luteolin; Molecules 13, 2628-51 (2008)
  9. Seelinger G, Merfort I, Schempp CM. Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin; Planta Med 74, 1667-77 (2008)
  10. Siedle B, Hrenn A, Merfort I. A review on natural compounds as inhibitors of human neutrophil elastase; Planta Med 73, 401-420 (2007)
  11. Merfort I. Arnika: Neue Erkenntnisse über eine alte Arzneipflanze; Internist Praxis 47, 369-376 (2007)
  12. Martin SF, Merfort I, Thierse HJ. Interaction of chemicals and metal ions with proteins and role for immune responses; Mini Review in Med Chem 6, 247-255 (2006)
  13. Merfort, I. Patented inhibitors (2002-2005) of the transcription factor NF-kB; Expert Opinion in Therapy 166, 797-810 (2006)
  14. Merfort I. Was man über Pflanzen und ihre kontaktallergene Wirkung wissen sollte. Z Phytother 24, 22-29 (2003)
  15. Merfort I. Arnika: Neue Erkenntnisse zum Wirkungsmechanismus einer traditionellen Heilpflanze; Forsch Komplementärmedizin und klassische Naturheilkunde 10 (Suppl. 1), 45-48 (2003)
  16. Pelzer S, Hoffmeister D, Merfort I, Bechthold A. Procaryotic and eucaryotic cells in biotech production; in Pharmaceutical Biotechnology, Drug Discovery and Clinical Applications; Wiley-VHC Verlag, Ed. Kayser, O., Müller, R.H. 9-33 (2003)
  17. Merfort I. Review on the analytical techniques of sesquiterpenes and sesquiterpene lactones; J. Chromatogr A 967, 115-130 (2002)
  18. Merfort, I. Heil- und Nutzpflanzen mit Hauttücken; Pharm Ztg 147, 96-101 (2002)
  19. Merfort I. Entzündungshemmende Wirkstoffe aus der Natur; Bioforum 3/2002, 138-140
  20. von Raison J, Heilmann J, Merfort I, Schmidt TJ, Brock FE, Leven W, Bomme U, Bauer R. Arnika - Arzneipflanze mit Tradition und Zukunft, Z Phytother 21, 39-54 (2000)
  21. Rüngeler P, Lyß G, Merfort I. Der Transkriptionsfaktor NF-kB - ein zentraler Mediator im Immunsystem und Entzündungsgeschehen; Pharm.Ztg 144: 100-108 (1999)
  22. Heilmann J, Merfort I. Aktueller Kenntnisstand zum Metabolismus von Flavonoiden. I. Resorption und Metabolismus von Flavonolen; Pharm. Unserer Zeit 27, 58-65 (1998)
  23. Heilmann J, Merfort I. Aktueller Kenntnisstand zum Metabolismus von Flavonoiden. II. Resorption und Metabolismus von Flavonen, Flavanonen, Flavanen, Proanthocyanidinen und Isoflavonoiden; Pharm. Unserer Zeit 27, 173-183 (1998)
  24. Willuhn G, Merfort I, Paßreiter CM, Schmidt TJ. Chemistry and systematics of the genus Arnica; Advances in Compositae systematics; Hrsg.: D.J.N. Hind, C. Jeffrey, G.V. Pope, The Royal Botanic Gardens, Kew, 1995, p. 167-195
  25. Hagers Handbuch der Pharmazeutischen Praxis, Bd. 4 - 6, Hrsg.: R. Hänsel, K. Keller, H. Rimpler, G. Schneider, Springer-Verlag, Monographs: Arnica, Bd. 4, 342 - 357, 1992; Levisticum, Bd. 5, 664 - 670, 1993; Orthosiphon, Bd. 5, 966 - 970, 1993; Symphoricarpos, Bd. 6, 853 - 854, 1994
  26. Merfort I, Heilmann J. 41. Jahrestagung der Gesellschaft für Arzneipflanzenforschung in Düsseldorf; Pharm. Unserer Zeit 22, 323-328 (1993)
  27. Merfort I, Schmidt E. Säuglings- und Kindertees, Pharmakologie und Anwendung,Sonderheft: Pädiatrische Praxis, Die Ernährung des Säuglings und Kindes, Haus Marseille Verlag, München, S. 153 - 164 (1989)
  28. ebenfalls erschienen in Erweiterte Schulmedizin, Bd. 1, Beiträge zur Phytotherapie, Hrsg. R. Saller, H. Feiereis, Haus Marseille Verlag, München, S. 81-92